Mammoth Comeback? Scientists Engineer Woolly Traits in Lab Mice
The Tiny Lab Mouse Making a Big Impact
A small lab mouse is set to play a significant role in scientific research. Genetically modified to exhibit several traits of the woolly mammoth, this mouse has curly whiskers and longer hair compared to ordinary lab mice. These changes could help scientists understand how certain traits contributed to the survival of mammoths in cold climates.
Colossal Biosciences' Ambitious Mission
Colossal Biosciences, a private company based in Dallas, is at the forefront of efforts to bring extinct animals back to life. Founded in 2021, the company has raised substantial funds to support their groundbreaking research. Their ultimate goal is to resurrect species like the mammoth, dodo, and Tasmanian tiger by editing the genomes of their closest living relatives.
Breaking Down the Woolly Mouse: Genetic Engineering Explained
To create the woolly mouse, scientists identified specific genetic differences between mammoths and their closest living relative, the Asian elephant. By targeting and editing genes related to hair length, texture, color, and body fat, researchers successfully produced a mouse with mammoth-like features. This process involved making multiple gene edits simultaneously to achieve the desired traits.
Expert Opinions: Praise and Criticism
The scientific community has mixed reactions to Colossal's work. Some experts commend the precise and efficient genetic changes made to the mice, viewing it as a significant advancement in gene editing. However, others criticize the research for not yet demonstrating whether the modified mice have enhanced cold tolerance, which is essential for replicating mammoth traits. The debate continues on the practical implications of this research.
Future Goals and Potential Environmental Benefits
Colossal Biosciences aims to introduce mammoth-like creatures into the Arctic to help slow the thawing of permafrost by compressing snow and grass. This could potentially mitigate the release of carbon trapped in these fragile ecosystems. The company plans to have the first woolly mammoth calves by 2028, moving closer to restoring extinct fauna to their natural habitats.
Conclusion: The Future of Extinct Animal Resurrection
Colossal Biosciences is pushing the boundaries of genetic engineering in its quest to bring back extinct species. While the creation of a woolly mouse marks a promising step, challenges remain in fully understanding and replicating the traits needed for survival in natural environments. The journey toward resurrecting the woolly mammoth and other extinct animals continues to capture scientific and public interest alike.
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cnn.com